Drugs / Lorigerlimab

Trials 9 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT05293496 Apr 2022 → Jun 2025 castration-resistant prostate carcinoma, hepatocellular carcinoma, malignant epithelial tumor of ovary, melanoma +2 MacroGenics Completed No outcome recorded
Phase 1 NCT03761017 Dec 2018 → Aug 2024 colorectal cancer, cutaneous melanoma, metastatic prostate carcinoma, non-small cell squamous lung carcinoma MacroGenics Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT07137390 Sep 2025 → Jan 2026 colorectal cancer M.D. Anderson Cancer Center Withdrawn No outcome recorded
Phase 26 trials
Phase 2 NCT07565155 Jun 2026 → Jun 2031 expected pancreatic ductal adenocarcinoma Peter Hosein, MD Not yet recruiting No outcome recorded
Phase 2 NCT07071961 Feb 2026 → May 2027 colorectal cancer M.D. Anderson Cancer Center Suspended No outcome recorded
Phase 2 NCT07223567 Oct 2025 → Jan 2026 rectal cancer M.D. Anderson Cancer Center Withdrawn No outcome recorded
Phase 2 NCT06730347 May 2025 → Jul 2027 expected cervical clear cell adenocarcinoma, endometrial cancer, fallopian tube clear cell adenocarcinoma, ovarian clear cell adenocarcinoma +3 MacroGenics Recruiting No outcome recorded
Phase 2 NCT05848011 Sep 2023 → Feb 2026 hormone-resistant prostate carcinoma MacroGenics Completed No outcome recorded
Phase 2 NCT05475171 Dec 2022 → Jun 2028 cervical cancer, metastatic malignant neoplasm M.D. Anderson Cancer Center Suspended No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 10 sources stand behind the page.

FieldValueCited text
Known as Lorigerlimab ClinicalTrials.gov intervention name — accepted as the source's own label NCT03761017
8

NCT07565155

NCT05475171

NCT07223567

NCT06730347

NCT05848011

NCT05293496

NCT07137390

NCT07071961

Known as AEX-1344 ChEMBL registry synonym — accepted as the source's own label CHEMBL5095278
Known as MGD-019 ChEMBL registry synonym — accepted as the source's own label CHEMBL5095278
Modality Protein / enzyme biologic “Bispecific DART protein” NCT03761017
Route Intravenous “administered IV” NCT03761017