drugset / Trial / NCT07137390

A Trial of Regorafenib Plus Lorigerlimab as Neoadjuvant Therapy for Patients With pMMR/MSS, Resectable, Lung-limited Metastatic Colorectal Cancer

NCT07137390

Phase 1/2 Withdrawn M.D. Anderson Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

To apply its findings as rationale needed for a subsequent registration trial towards a novel indication for systemic treatment of resectable, lung-limited metastatic CRC.

Timeline

Start
2025-09-03
Primary completion
2026-01-22
Completion
2026-01-22

Drugs

EvaluationDrugModalityDoseRoute
Subject Lorigerlimab Protein / enzyme biologic Oral
Subject Regorafenib Small molecule Oral

Indications