drugset / Trial / NCT07074496
Efficacy, Safety, and Pharmacokinetics of ThisCART19A Combined With Olverembatinib in Patients With Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia.
Phase 0
Recruiting
20 enrolled
The First Affiliated Hospital of Soochow University
Fundamenta Therapeutics, Ltd. · collab
NaSingle-groupOpen-labelTreatment
Summary
This is an Open, Prospective, Single-arm Study, which is designed to evaluate the efficacy, safety and pharmacokinetics of ThisCART19A Combined With Olverembatinib for the treatment of Newly Diagnosed Ph-positive lymphoblastic leukemia.
Timeline
- Start
- 2024-01-01
- Primary completion
- 2025-11-15
- Completion
- 2028-07-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Olverembatinib | Small molecule | — | Oral |
| Subject | ThisCART19A | Cell therapy | — | Intravenous |
| Background | Cyclophosphamide | Other / unclassified | — | — |
| Background | Fludarabine | Small molecule | — | — |