drugset / Trial / NCT07093554

Cilta-Talq Fusion Study: A Phase 1b Study of Talquetamab Bridging Therapy Followed by Ciltacabtagene Autoleucel in Patients With Relapsed/Refractory Multiple Myeloma

NCT07093554

Phase 1 Recruiting 31 enrolled Medical College of Wisconsin
NaSingle-groupOpen-labelTreatment

Summary

This is a single-arm, open-label, phase 1b study evaluating the safety and feasibility of using talquetamab as bridging therapy prior to cilta-cel in patients with relapsed and refractory multiple myeloma (RRMM).

Timeline

Start
2025-12-02
Primary completion
2027-07-01
Completion
2028-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Talquetamab Monoclonal antibody Subcutaneous
Subject ciltacabtagene autoleucel Cell therapy Intravenous

Indications