drugset / Trial / NCT07095933

The Safety and Efficacy Evaluation of Everolimus as an Adjunctive Treatment for Focal Refractory Epilepsy

NCT07095933

Phase 0 Recruiting 5 enrolled Xuanwu Hospital, Beijing
NaSingle-groupOpen-labelTreatment

Summary

The aim of this study is to evaluate the clinical efficacy of everolimus as an adjunctive therapy for refractory epilepsy. The significance lies in addressing whether the mTOR inhibitor sirolimus has antiepileptic adjunctive effects for a broader range of patients with refractory epilepsy, with the hope of providing a new mTOR-targeted antiepileptic adjunctive medication regimen that is administered only during epileptic events and can be widely used for various types of refractory epilepsy.

Timeline

Start
2026-07-01
Primary completion
2026-12-01
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Everolimus Small molecule 2.5 mg Oral
Subject Everolimus Small molecule 5 mg Oral
Subject Everolimus Small molecule 7.5 mg Oral

Indications