drugset / Trial / NCT07099391

A Study of Dara-RVd and Teclistamab-RVd in People With Multiple Myeloma

NCT07099391

Phase 1/2 Recruiting 65 enrolled Memorial Sloan Kettering Cancer Center
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to find out whether Tec-RVd (teclistamab, lenalidomide, bortezomib, and dexamethasone) after 3 treatment Cycles of Dara-RVd (daratumumab, lenalidomide, bortezomib, and dexamethasone) is a safe treatment for people with newly diagnosed multiple myeloma (MM).

Timeline

Start
2025-07-24
Primary completion
2029-07-24
Completion
2029-07-24

Drugs

EvaluationDrugModalityDoseRoute
Subject Daratumumab Monoclonal antibody
Subject Teclistamab Monoclonal antibody
Background Bortezomib Small molecule
Background Dexamethasone Small molecule
Background Lenalidomide Other / unclassified

Indications