drugset / Trial / NCT07101250

Preoperative Acetazolamide

NCT07101250

Phase 4 Recruiting 100 enrolled Prisma Health-Upstate
RandomizedParallel-groupDouble-blindOther

Summary

The goal of this randomized study looks at whether giving patients a medicine called acetazolamide (also called Diamox) before they have laparoscopic hysterectomy may decrease postoperative pain. Researchers will compare acetazolamide to a placebo or inactive drug, to see if acetazolamide helps the pain that may occur after surgery from the gas used in the abdomen during the laparoscopic procedure. Patients will be asked to rate their pain before surgery and after surgery through 24 hours.

Timeline

Start
2025-10-30
Primary completion
2026-08-01
Completion
2026-11-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Acetazolamide Small molecule 500 mg Oral