drugset / Trial / NCT07113964

QL1706 With Olaparib for Previously Treated HER2-negative Breast Cancer Patients With Homologous Recombination Deficiency (HRD)

NCT07113964

Phase 2 Not yet recruiting 79 enrolled The First Affiliated Hospital with Nanjing Medical University
NaSingle-groupOpen-labelTreatment

Summary

This study will evaluate the safety and efficacy of QL1706 and Olaparib in human epidermal growth factor receptor 2 (HER2)-negative unresectable and/or metastatic breast cancer who had received 2-4 line of prior systematic therapy.

Timeline

Start
2025-08-30
Primary completion
2027-03-30
Completion
2029-03-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Olaparib Small molecule
Subject QL1706 Monoclonal antibody