drugset / Trial / NCT07125911

Effect of Common Analgesia on Pulp Sensibility

NCT07125911

Completed 122 enrolled HITEC-Institute of Medical Sciences
RandomizedParallel-groupTriple-blindDiagnostic

Summary

his study will investigate whether commonly used analgesics - 400 mg ibuprofen and 500 mg paracetamol - influence the accuracy of pulpal sensibility tests (cold test and electric pulp test) in patients with symptomatic irreversible pulpitis. Analgesics are often taken prior to dental visits and may mask endodontic symptoms, affecting diagnosis. Participants will be randomly assigned to receive either ibuprofen or paracetamol in a double-blind design. Test responses and pain levels will be measured before and 30 minutes after medication to assess any masking effect.

Timeline

Start
2024-04-07
Primary completion
2025-04-07
Completion
2025-04-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Acetaminophen Small molecule 500 mg Oral
Subject Ibuprofen Small molecule 400 mg Oral