drugset / Trial / NCT07125911
Effect of Common Analgesia on Pulp Sensibility
RandomizedParallel-groupTriple-blindDiagnostic
Summary
his study will investigate whether commonly used analgesics - 400 mg ibuprofen and 500 mg paracetamol - influence the accuracy of pulpal sensibility tests (cold test and electric pulp test) in patients with symptomatic irreversible pulpitis. Analgesics are often taken prior to dental visits and may mask endodontic symptoms, affecting diagnosis. Participants will be randomly assigned to receive either ibuprofen or paracetamol in a double-blind design. Test responses and pain levels will be measured before and 30 minutes after medication to assess any masking effect.
Timeline
- Start
- 2024-04-07
- Primary completion
- 2025-04-07
- Completion
- 2025-04-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acetaminophen | Small molecule | 500 mg | Oral |
| Subject | Ibuprofen | Small molecule | 400 mg | Oral |