drugset / Trial / NCT07125937

Silver Diamine Flouride in Arresting Enamel Caries

NCT07125937

Completed 250 enrolled HITEC-Institute of Medical Sciences
NaSingle-groupOpen-labelTreatment

Summary

This interventional study aims to evaluate the effectiveness of 38% Silver Diamine Fluoride (SDF) in arresting enamel caries in adults aged 18-50 years. Dental caries is a biofilm-mediated, multifactorial disease that can cause progressive tooth damage. Conventional treatments are invasive and costly, whereas SDF offers a non-invasive, low-cost alternative. A total of 250 patients meeting the inclusion criteria will be treated with SDF following the UCSF protocol. Lesions will be evaluated clinically using ICDAS and radiographically using ICCMS at 3 weeks and 3 months post-intervention. The primary outcome is the proportion of enamel caries lesions arrested after treatment. Data will be analyzed using the chi-square test.

Timeline

Start
2024-05-07
Primary completion
2025-05-07
Completion
2025-05-07

Drugs

EvaluationDrugModalityDoseRoute
Subject silver diammine fluoride Small molecule 38 % Topical

Indications