drugset / Trial / NCT07131579
Intravenous Regional Analgesia of Dexmedetomidine
RandomizedParallel-groupDouble-blindPrevention
Summary
Dexmedetomidine is a highly selective α₂-adrenergic receptor agonist that exerts its effects by inhibiting the release of norepinephrine at presynaptic nerve terminals, leading to reduced sympathetic activity; This mechanism results in analgesia, sedation, and anxiolysis without significant respiratory depression
Timeline
- Start
- 2026-01-12
- Primary completion
- 2026-12-30
- Completion
- 2027-08-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexmedetomidine | Other / unclassified | 0.5 ug/kg | Intravenous |
Indications
No indication recorded.