drugset / Trial / NCT07133776

Application of PD-1 Inhibitors Combined With Tenofovir, Chidamide and Lenalidomide in the Treatment of EBV-associated Diseases.

NCT07133776

Phase 1/2 Not yet recruiting 30 enrolled The Affiliated Hospital of Xuzhou Medical University
NaSingle-groupOpen-labelTreatment

Summary

Currently, treatment options for Epstein-Barr virus (EBV) infection are limited, with unsatisfactory efficacy and no established standard therapy. Therefore, our center is conducting a prospective, multicenter, single-arm clinical trial to evaluate the efficacy and safety of PD-1 inhibitor in combination with tenofovir, chidamide, and lenalidomide in patients with EBV infectious diseases, aiming to provide a more effective and safer therapeutic option for EBV infectious diseases.

Timeline

Start
2025-09-01
Primary completion
2027-09-01
Completion
2027-09-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Lenalidomide Other / unclassified
Subject Tenofovir Small molecule
Subject Tucidinostat Small molecule