drugset / Trial / NCT07140211
Short-term Low-dose Low-molecular-weight Heparin to Prevent Postpartum Thrombosis
RandomizedParallel-groupSingle-blindPrevention
Summary
The goal of this clinical trial is to evaluate the risk-benefit of a short-term treatment with a low-dose low-molecular-weight heparin (LMWH), in the postpartum period (after delivery). The main questions it aims to answer are: * compared to no treatment, does short-term postpartum LMWH modify the risk of venous thromboembolism within 90 days of delivery? * compared to no treatment, does short-term postpartum LMWH modify the risks of bleeding and wound complications? Participants will take low-dose LMWH for 7-10 days or no treatment, and will be followed for 90 days post-delivery.
Timeline
- Start
- 2025-10-15
- Primary completion
- 2030-08
- Completion
- 2030-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dalteparin sodium | Other / unclassified | 5000 iu | — |
| Subject | Dalteparin sodium | Other / unclassified | 7500 iu | — |
| Subject | Enoxaparin sodium | Other / unclassified | 4000 iu | — |
| Subject | Enoxaparin sodium | Other / unclassified | 6000 iu | — |
| Subject | Nadroparin Calcium | Other / unclassified | 3800 iu | — |
| Subject | Nadroparin Calcium | Other / unclassified | 5700 iu | — |
| Subject | Tinzaparin | Other / unclassified | 4500 iu | — |
| Subject | Tinzaparin | Other / unclassified | 7000 iu | — |