drugset / Trial / NCT07141511

A Study to Investigate the Relative Bioavailability and Food Effect of a Fixed-Dose Combination Tablet Containing Zanubrutinib and Sonrotoclax (BG-71332) in Healthy Adults

NCT07141511

Phase 1 Completed 24 enrolled BeOne Medicines
RandomizedSequentialOpen-labelOther

Summary

The purpose of this study is to evaluate the relative bioavailability of a fixed-dose combination tablet containing zanubrutinib and sonrotoclax (BG-71332) compared to a zanubrutinib capsule and sonrotoclax tablet administered simultaneously and the effect of food on how the body processes the fixed-dose combination tablet.

Timeline

Start
2025-09-24
Primary completion
2026-02-23
Completion
2026-02-23

Drugs

EvaluationDrugModalityDoseRoute
Subject BG-71332 Unknown Oral
Subject Sonrotoclax Other / unclassified Oral
Subject Zanubrutinib Small molecule Oral

Indications

No indication recorded.