drugset / Trial / NCT07151872

Combination of QLS31905 and Chemotherapy ± QL2107 in Patients With CLDN18.2-positive Advanced Biliary Tract Cancer

NCT07151872

Phase 2 Not yet recruiting 120 enrolled Qilu Pharmaceutical Co., Ltd.
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This is an open-label, multicenter Phase II clinical study aimed at evaluating the efficacy, safety, PK profile, and immunogenicity of QLS31905 for Injection combined with Chemotherapy ± QL2107 in Patients with CLDN18.2-positive Advanced Biliary Tract Cancer

Timeline

Start
2025-09
Primary completion
2026-10
Completion
2026-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Capecitabine Small molecule
Subject Cisplatin Other / unclassified
Subject Gemcitabine Small molecule
Subject Oxaliplatin Small molecule
Subject QL2107 Unknown
Subject QLS31905 Unknown

Indications