drugset
drugset / Trial / NCT07153744

Efficacy and Safety of Shexiang Baoxin Pill(MUSKARDIA) in the Treatment of Acute Myocardial Infarction

NCT07153744 ↗

Phase 4 Not yet recruiting 9588 enrolled Shanghai Hutchison Pharmaceuticals Limited Affiliated Hospital of Jiangsu University · collabAffiliated Hospital of Shandong University of Traditional Chinese Medicine · collabAnkang Central Hospital · collabAnsteel Group General Hospital · collabAnyang Area Hospital of Puyang City · collabBeijing Chao Yang Hospital · collabBeijing Electric Power Hospital · collabBeijing Friendship Hospital · collabCangzhou Central Hospital · collabChangzhi Medical College · collabChaohu Hospital of Anhui Medical University · collabCivil Aviation General Hospital · collabDazhou First People's Hospital · collabFirst Affiliated Hospital of Fujian Medical University · collabFirst Affiliated Hospital of Nanyang Medical College · collabFirst Affiliated Hospital of Ningbo University · collabFirst People's Hospital of Chenzhou · collabGUI LIN PEOPLE'S HOSPITAL · collabGeneral Hospital of Fuxin Mining Industry Group of Liaoning Health Industry Group · collabGeneral Hospital of Ningxia Medical University · collabHandan Central Hospital · collabHuai'an First People's Hospital · collabHuaibei Miners General Hospital · collabHuaihe Hospital of Henan University · collabHuang Shan People's Hospital · collabHuashan Hospital · collabInner Mongolia Autonomous Region People's Hospital · collabJi'an Central People's Hospital · collabJiangxi Provincial People's Hopital · collabJiaozuo Second People's Hospital · collabJilin Province People's Hospital · collabJingzhou Central Hospital · collabJinhua Central Hospital · collabJining First People's Hospital · collabLanzhou University Second Hospital · collabLinFen People's Hospital · collabLinyi People's Hospital · collabLonghua Hospital · collabNorth China University of Science and Technology · collabPeking University People's Hospital · collabPeople's Hospital of Chongqing · collabPeople's Hospital of Quzhou · collabQianfoshan Hospital · collabRenmin Hospital of Wuhan University · collabRizhao People's Hospital · collabSecond Affiliated Hospital of Soochow University · collabSecond Affiliated Hospital, School of Medicine, Zhejiang University · collabSecond Xiangya Hospital of Central South University · collabShandong Provincial Hospital · collabShanghai 10th People's Hospital · collabShanghai 6th People's Hospital · collabShanghai East Hospital · collabShanghai General Hospital, Shanghai Jiao Tong University School of Medicine · collabShanghai Zhongshan Hospital · collabShanxi Cardiovascular Hospital · collabShaoguan People's Hospital · collabShijiazhuang People's Hospital · collabShuguang Hospital of Shanghai University of Traditional Chinese Medicine · collabSir Run Run Shaw Hospital · collabTaizhou Enze Medical Center Group · collabThe Affiliated Hospital Of Southwest Medical University · collabThe Affiliated Hospital of Qingdao University · collabThe Central Hospital of Shaoyang · collabThe First Affiliated Hospital of Anhui Medical University · collabThe First Affiliated Hospital of Dalian Medical University · collabThe First Affiliated Hospital of Guangdong Pharmaceutical University · collabThe First Affiliated Hospital of Henan University of Science and Technology · collabThe First Affiliated Hospital of Nanchang University · collabThe First Affiliated Hospital of University of South China · collabThe First Affiliated Hospital of Zhengzhou University · collabThe First Affiliated Hospital with Nanjing Medical University · collabThe First Hospital of Hebei Medical University · collabThe First People's Hospital of Changde City · collabThe First People's Hospital of Chu Zhou · collabThe First People's Hospital of Lianyungang · collabThe First People's Hospital of Nanning · collabThe People's Hospital of JiangMen · collabThe People's Hospital of Jizhou District, Tianjin · collabThe People's Hospital of Langfang City · collabThe Second Affiliated Hospital of Fujian Medical University · collabThe Second Affiliated Hospital of Hainan Medical University · collabThe Southwest Hospital of Army Medical University · collabThe Third Affiliated Hospital of Guangzhou Medical University · collabThe Third Affiliated Hospital of Wenzhou Medical University · collabThe Third People's Hospital of Chengdu · collabThe Tirst People's Hospital of Mianyang · collabThe second People's Hospital of Guiyang · collabTianjin Third Central Hospital · collabTongling People's Hospital · collabWeifang People's Hospital · collabWeihai Municipal Hospital · collabWuhan No.1 Hospital · collabWuxi People's Hospital · collabXiangya Hospital of Central South University · collabXiangyang Central Hospital · collabXingtai Central Hospital · collabXuancheng People's Hospital · collabXuanwu Hospital, Beijing · collabXuzhou New Health Hospital · collabYan'an Affiliated Hospital of Kunming Medical University · collabYangchun People's Hospital · collabYueyang Central Hospital · collabZhoukou Central Hospital · collabZhuZhou Central Hospital · collabthe First Hospital of Anhui University of Science and Technology · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

This study aims to evaluate the value of Shexiang Baoxin Pill (MUSKARDIA) in patients with acute myocardial infarction (AMI) through a prospective, multicenter, pragmatic randomized controlled real-world study. It seeks to validate its efficacy in reducing cardiovascular event risk during the peri-PCI period, as well as its effects on cardiac function, quality of life , and relevant biomarkers. Through this research, we expect to provide higher-quality evidence for the application of SBP in AMI patients undergoing PCI, thereby further optimizing comprehensive treatment strategies for AMI.

Timeline

Start
2025-09-01
Primary completion
2028-12
Completion
2029-12-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Aspirin Small molecule — —
Subject Shexiang Baoxin Pill Traditional medicine (herbal / TCM) 2 unknown Oral
Subject Shexiang Baoxin Pill Traditional medicine (herbal / TCM) 4 unknown Oral

Indications

acute myocardial infarction