drugset / Trial / NCT07158411
Evaluate the Effect of Vimseltinib on Organic Cation Transporter 2 (OCT2)
NaSequentialOpen-labelBasic science
Summary
The main purpose of this study is to evaluate the effect of multiple doses of vimseltinib on the pharmacokinetics (PK) of a clinical OCT2 substrate (metformin) in healthy male participants. This study will also assess the safety and tolerability when vimseltinib is co-administered with the clinical OCT2 substrate (metformin) in healthy male participants. This study will last approximately 25 days.
Timeline
- Start
- 2025-11-20
- Primary completion
- 2026-01-30
- Completion
- 2026-01-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metformin | Small molecule | — | Oral |
| Subject | Vimseltinib | Small molecule | — | Oral |
Indications
No indication recorded.