drugset / Trial / NCT07161414
A Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Rilvegostomig in Adult Participants With Advanced Solid Tumors Previously Treated With Standard of Care Therapy
RandomizedSequentialOpen-labelTreatment
Summary
The purpose of this study is to determine the subcutaneous (SC) dose that gives rilvegostomig exposure comparable to the intravenous (IV) exposure, and to evaluate the pharmacokinetics (PK) and safety of SC rilvegostomig in adult participants with advanced solid tumors previously treated with standard of care therapy for whom immunooncology (IO) monotherapy would be deemed appropriate by the investigator.
Timeline
- Start
- 2025-11-25
- Primary completion
- 2027-07-19
- Completion
- 2029-07-24
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Rilvegostomig | Other / unclassified | — | Intravenous |
| Background | rHuPH20 | Protein / enzyme biologic | — | Subcutaneous |