Drugs / Rilvegostomig

Trials 33 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 02 trials
Phase 0 NCT06366451 May 2024 → Mar 2026 head and neck squamous cell carcinoma Presage Biosciences Completed No outcome recorded
Phase 0 NCT04541108 Jul 2021 → Dec 2031 expected cancer Presage Biosciences Active not recruiting No outcome recorded
Phase 14 trials
Phase 1 NCT07161414 Nov 2025 → Jul 2027 expected cancer AstraZeneca Recruiting No outcome recorded
Phase 1 NCT04686305 Mar 2021 → Jun 2027 expected non-small cell lung carcinoma AstraZeneca Recruiting No outcome recorded
Phase 1 NCT04612751 Feb 2021 → May 2026 overdue non-small cell lung carcinoma AstraZeneca Active not recruiting No outcome recorded
Phase 1 NCT03819465 Dec 2018 → May 2023 overdue non-small cell lung carcinoma AstraZeneca Active not recruiting No outcome recorded
Phase 1/24 trials
Phase 1/2 NCT06996782 Nov 2025 → Feb 2029 expected non-small cell lung carcinoma AstraZeneca Recruiting No outcome recorded
Phase 1/2 NCT07115043 Jul 2025 → Oct 2029 expected cutaneous neuroendocrine carcinoma, gastroesophageal cancer, head and neck squamous cell carcinoma, melanoma +5 AstraZeneca Recruiting No outcome recorded
Phase 1/2 NCT05123482 Oct 2021 → Sep 2027 expected biliary tract cancer, breast carcinoma, endometrial cancer, non-small cell squamous lung carcinoma +1 AstraZeneca Recruiting No outcome recorded
Phase 1/2 NCT04995523 Sep 2021 → Aug 2026 overdue non-small cell lung carcinoma AstraZeneca Active not recruiting No outcome recorded
Phase 211 trials
Phase 2 NCT07128290 Oct 2025 → Apr 2029 expected intrahepatic cholangiocarcinoma Federation Francophone de Cancerologie Digestive Not yet recruiting No outcome recorded
Phase 2 NCT07098338 Aug 2025 → Apr 2029 expected non-small cell lung carcinoma AstraZeneca Recruiting No outcome recorded
Phase 2 NCT07069712 Jul 2025 → Jan 2027 expected gastroesophageal adenocarcinoma AstraZeneca Recruiting No outcome recorded
Phase 2 NCT06630130 Jan 2025 → Oct 2028 expected gastric cancer Jeeyun Lee Recruiting No outcome recorded
Phase 2 NCT06569225 Dec 2024 → Dec 2027 expected cholangiocarcinoma University Health Network, Toronto Not yet recruiting No outcome recorded
Phase 2 NCT05414032 Jul 2023 → Sep 2027 expected head and neck squamous cell carcinoma University Health Network, Toronto Recruiting No outcome recorded
Phase 2 NCT05775159 Apr 2023 → Oct 2026 expected biliary tract cancer, hepatocellular carcinoma AstraZeneca Active not recruiting No outcome recorded
Phase 2 NCT05702229 Jan 2023 → Nov 2027 expected gastric cancer AstraZeneca Recruiting No outcome recorded
Phase 2 NCT05061550 Apr 2022 → May 2030 expected non-small cell lung carcinoma AstraZeneca Recruiting No outcome recorded
Phase 2 NCT04379596 Jun 2020 → Jun 2027 expected gastric cancer AstraZeneca Recruiting No outcome recorded
Phase 312 trials
Phase 3 NCT07431281 Feb 2026 → Aug 2029 expected esophageal cancer, gastric cancer, gastroesophageal junction adenocarcinoma AstraZeneca Recruiting No outcome recorded
Phase 3 NCT07221253 Dec 2025 → Jul 2029 expected biliary tract cancer AstraZeneca Recruiting No outcome recorded
Phase 3 NCT06921785 May 2025 → Mar 2029 expected hepatocellular carcinoma AstraZeneca Recruiting No outcome recorded
Phase 3 NCT06868277 Apr 2025 → Jan 2030 expected non-small cell lung carcinoma AstraZeneca Recruiting No outcome recorded
Phase 3 NCT06989112 Mar 2025 → Jan 2029 expected endometrial cancer AstraZeneca Recruiting No outcome recorded
Phase 3 NCT06764875 Mar 2025 → Apr 2029 expected gastroesophageal junction adenocarcinoma AstraZeneca Recruiting No outcome recorded
Phase 3 NCT06627647 Nov 2024 → Nov 2030 expected non-small cell lung carcinoma AstraZeneca Recruiting No outcome recorded
Phase 3 NCT06692738 Nov 2024 → Jul 2030 expected non-small cell lung carcinoma AstraZeneca Recruiting No outcome recorded
Phase 3 NCT06564844 Oct 2024 → Jun 2027 expected non-small cell lung carcinoma AstraZeneca Active not recruiting No outcome recorded
Phase 3 NCT06467357 Aug 2024 → Jun 2028 expected biliary tract cancer AstraZeneca Recruiting No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT05489211 Background Sep 2022 → Oct 2027 expected biliary tract cancer, castration-resistant prostate carcinoma, colorectal cancer, endometrial cancer +3 AstraZeneca Recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 34 sources stand behind the page.

FieldValueCited text
Known as Rilvegostomig ClinicalTrials.gov intervention name — accepted as the source's own label NCT07069712
29

NCT07115043

NCT06764875

NCT06627647

NCT05489211

NCT06467357

NCT01042379

NCT06996782

NCT06692738

NCT04686305

NCT06366451

NCT05775159

NCT06357533

NCT04379596

NCT04541108

NCT07431281

NCT06868277

NCT07221253

NCT06921785

NCT07098338

NCT05123482

NCT06569225

NCT07128290

NCT06989112

NCT05061550

NCT05702229

NCT06630130

NCT07161414

NCT06109779

NCT06564844

Known as AZD2936 “AZD8205 and AZD2936 (Rilvegostomig)” NCT05123482
5

“Rilvegostomig (AZD2936)” NCT06692738

NCT04612751

NCT04995523

NCT03819465

NCT05414032

Action Inhibit “In the preclinical studies, dual blockade of TIGIT and PD 1 by AZD2936 enhanced human T cell function and promoted antitumor immune responses.” NCT05414032
Modality Other / unclassified “Rilvegostomig is a bispecific antibody” NCT05123482
Route Intravenous “Rilvegostomig: 750mg IV Q3W” NCT01042379
Target TIGIT “Rilvegostomig is a bispecific antibody that specifically binds to human TIGIT and PD-1” NCT05123482