drugset / Trial / NCT07098338

A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)

NCT07098338

Phase 2 Recruiting 278 enrolled AstraZeneca Daiichi Sankyo · collab
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a Phase II, multi-center, open-label platform study evaluating novel combination treatment options in participants with locally advanced or metastatic NSCLC. The study will consist of several sub-studies, each evaluating the safety, tolerability, and preliminary antitumour activity of various treatment combinations. This study will be conducted in approximately 80 centers globally across 10 countries.

Timeline

Start
2025-08-07
Primary completion
2029-04-06
Completion
2029-04-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Datopotamab deruxtecan Monoclonal antibody Intravenous
Subject Ramucirumab Monoclonal antibody Intravenous
Subject Rilvegostomig Other / unclassified Intravenous