drugset / Trial / NCT07098338
A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)
Non-randomizedSequentialOpen-labelTreatment
Summary
This is a Phase II, multi-center, open-label platform study evaluating novel combination treatment options in participants with locally advanced or metastatic NSCLC. The study will consist of several sub-studies, each evaluating the safety, tolerability, and preliminary antitumour activity of various treatment combinations. This study will be conducted in approximately 80 centers globally across 10 countries.
Timeline
- Start
- 2025-08-07
- Primary completion
- 2029-04-06
- Completion
- 2029-04-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Datopotamab deruxtecan | Monoclonal antibody | — | Intravenous |
| Subject | Ramucirumab | Monoclonal antibody | — | Intravenous |
| Subject | Rilvegostomig | Other / unclassified | — | Intravenous |