drugset / Trial / NCT07174427

Multi-center Study of TBI-1301 (INN: Mipetresgene Autoleucel; Mip-cel) in Patients With NY-ESO-1 Positive Synovial Sarcoma

NCT07174427

Phase 3 Recruiting 5 enrolled Takara Bio Inc.
NaSequentialOpen-labelTreatment

Summary

The purpose of this study is to verify the safety and the efficacy of TBI-1301 for NY-ESO-1 expressing synovial sarcoma when administered following cyclophosphamide/fludarabine pre-treatment.

Timeline

Start
2026-01-05
Primary completion
2032-03
Completion
2032-03

Drugs

EvaluationDrugModalityDoseRoute
Subject TBI-1301 Cell therapy 5e+09 cells Intravenous
Background Cyclophosphamide Other / unclassified 750 mg/m2 Intravenous
Background Fludarabine Small molecule 30 mg/m2 Intravenous

Indications