drugset / Trial / NCT07178639

Comparing Efficacy of Bromfenac 0.09%, Nepafenac 0.3% and Diclofenac 0.1% in Patients After Cataract Surgery

NCT07178639

Recruiting 150 enrolled Nemocnice Kolín
RandomizedParallel-groupOpen-labelPrevention

Summary

The goal of this clinical trial is to learn which of the drugs bromfenac 0.09%, nepafenac 0.3% and diclofenac 0.1% has better efficacy in treatment and prevention of cystoid macular oedema after cataract surgery. The main questions it aims to answer are: Which of the drugs has better efficacy in macular oedema prevention? What medical problems do participants have when taking different drugs? Researchers will compare drugs to each other. Participants will: Take on of the drugs (randomized) as their treatment in preoperative and postoperative period. Visit the clinic after the surgery on the first day, first week, in three weeks and in six weeks. Undergo retina examination with OCT (optical coherence tomography), best vision, and fill in forms considering their quality of life.

Timeline

Start
2025-08-01
Primary completion
2026-02-28
Completion
2026-02-28

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bromfenac Other / unclassified 0.09 % Other
Comparator Diclofenac Other / unclassified 0.1 % Other
Comparator Nepafenac Other / unclassified 0.3 % Other