Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery.

Phase 1/2 Not yet recruiting 60 enrolled Liaquat National Hospital & Medical College

RandomizedParallel-groupQuadruple-blindSupportive care

Summary

This study aims to compare intranasal dexmedetomidine versus intranasal ketamine as a premedication in children undergoing surgery in our population. Hypothesis is Intranal dexmedetomidine is better than intranasal ketamine in producing preoperative sedation in pediatric patients undergoing surgery under general anesthesia.

Timeline

Start: 2026-01-01
Primary completion: 2026-06-30
Completion: 2026-07-30

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Dexmedetomidine	Other / unclassified	2 ug/kg	Intranasal
Subject	Ketamine	Small molecule	2 mg/kg	Intranasal

Indications

No indication recorded.