drugset / Trial / NCT07184788

G-Pola-GemOx in Refractory/Relapsed Aggressive B-Cell Lymphoma

NCT07184788

Phase 2 Not yet recruiting 80 enrolled Navy General Hospital, Beijing
NaSingle-groupOpen-labelTreatment

Summary

The goal of this phase 2 trial is to test the safety and efficacy of G-Pola-GemOx as induction therapy in patients with Refractory/Relapsed Aggressive B-Cell Lymphoma.

Timeline

Start
2025-10-01
Primary completion
2030-10-01
Completion
2031-10-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Gemcitabine Small molecule 1000 mg/m2 Intravenous
Subject Glofitamab Monoclonal antibody 30 mg
Subject Oxaliplatin Small molecule 100 mg/m2 Intravenous
Subject Polatuzumab Vedotin Other / unclassified 1.8 mg/kg Intravenous