drugset / Trial / NCT07186062

Clinical Outcomes of Levosimendan Versus Dobutamine Versus Milrinone in Cases With Acute Decompensated Heart Failure With Impaired Renal Function

NCT07186062 ↗

Phase 4 Completed 60 enrolled Ain Shams University
RandomizedParallel-groupDouble-blindTreatment

Summary

This study aimed to assess and compare the cardiac, renal, and clinical efficacy of Levosimendan (LEV), Dobutamine (DOB), and milrinone (MIL) in cases with acute decompensated heart failure (ADHF) complicated by renal impairment, with a focus on their role in the management of cardiorenal syndrome (CRS).

Timeline

Start
2022-06-01
Primary completion
2024-06-01
Completion
2024-06-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dobutamine Small molecule 20 ug/kg —
Comparator Levosimendan Other / unclassified — —
Comparator Milrinone Small molecule — Intravenous

Indications