drugset / Trial / NCT07186062
Clinical Outcomes of Levosimendan Versus Dobutamine Versus Milrinone in Cases With Acute Decompensated Heart Failure With Impaired Renal Function
RandomizedParallel-groupDouble-blindTreatment
Summary
This study aimed to assess and compare the cardiac, renal, and clinical efficacy of Levosimendan (LEV), Dobutamine (DOB), and milrinone (MIL) in cases with acute decompensated heart failure (ADHF) complicated by renal impairment, with a focus on their role in the management of cardiorenal syndrome (CRS).
Timeline
- Start
- 2022-06-01
- Primary completion
- 2024-06-01
- Completion
- 2024-06-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dobutamine | Small molecule | 20 ug/kg | — |
| Comparator | Levosimendan | Other / unclassified | — | — |
| Comparator | Milrinone | Small molecule | — | Intravenous |