drugset / Trial / NCT07187583
Tapering of Biologics in Chronic Rhinosinusitis With Nasal Polyps
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to investigate the feasibility of extending the dosing intervals of biological therapies while maintaining optimal treatment effects in chronic rhinosinusitis with nasal polyps (CRSwNP).
Timeline
- Start
- 2025-06-05
- Primary completion
- 2028-03-01
- Completion
- 2028-03-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dupilumab | Monoclonal antibody | 300 mg | Subcutaneous |
| Comparator | Mepolizumab | Monoclonal antibody | 100 mg | Subcutaneous |