drugset / Trial / NCT07187869

Modulation of the Bone Immune Microenvironment Following Cabozantinib Treatment of Bone Metastatic Clear Cell Renal Cell Carcinoma: Proof of Concept Study

NCT07187869

Phase 1 Not yet recruiting 16 enrolled M.D. Anderson Cancer Center Exelixis · collab
NaSingle-groupOpen-labelTreatment

Summary

The goal of our study is to explore how treatments affect the bone immune microenvironment and determine the best treatment options for patients with metastatic kidney cancer to the bone. This could prevent skeletal complications and improve patient outcomes.

Timeline

Start
2026-03-31
Primary completion
2027-04-07
Completion
2029-04-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Cabozantinib Small molecule Intravenous
Background Nivolumab Monoclonal antibody Intravenous