drugset / Trial / NCT07188909
Clinical Observation on the Efficacy of Patient-Donor Derived Probiotics in Improving Intestinal Flora Disorder in Patients With Intestinal Acute Graft-Versus-Host Disease (aGVHD)
NaSingle-groupOpen-labelTreatment
Summary
To clinically evaluate the efficacy of patient- and/or donor-derived probiotics in ameliorating intestinal flora dysbiosis in patients with acute intestinal graft-versus-host disease (aGVHD), thereby mechanistically enhancing clinical outcomes and quality of life through intestinal microbiome modulation.
Timeline
- Start
- 2025-09-15
- Primary completion
- 2026-03-04
- Completion
- 2026-03-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | BIFIDOBACTERIUM SPP. | Other / unclassified | — | — |
| Subject | Lactobacillus | Unknown | — | — |