Effect of Locally Applied Simvastatin Gel on Dental Implant Stability and Marginal Bone Level

Summary

stability and marginal bone level. Forty-two patients received dental implants and were randomly assigned to two groups. In the test group, 1.2% simvastatin in 4% methylcellulose gel was applied around the implant, while in the control group, methylcellulose gel alone was used. Implant stability was measured using resonance frequency analysis at baseline, 8 weeks, and 16 weeks. Marginal bone level was assessed by cone-beam computed tomography (CBCT) at baseline and 16 weeks. The aim of the study was to investigate whether local application of simvastatin enhances osseointegration and reduces marginal bone loss compared to the control treatment.

Timeline

Start

2024-10-03

Primary completion

2025-07-06

Completion

2025-07-06

Drugs

Indications

No indication recorded.