drugset / Trial / NCT07195149
Comparing High and lOw-dose asPirin With Dual anTIplatelet Therapy for Three Months Using prasUgrel and aSpirin Following Coronary Artery Bypass Grafting. (OPTIMUS-CABG Trial)
Phase 3
Recruiting
1703 enrolled
Dolnośląskie Centrum Chorób Serca im.prof. Zbigniewa Religi MEDINET Sp. z o.o.
Medical Research Agency, Poland · collab
RandomizedParallel-groupOpen-labelPrevention
Summary
The purpose of this study is to compare the effect of prasugrel plus low-dose aspirin versus high dose aspirin alone (300mg) and versus low dose aspirin alone (75 mg) in patients with chronic coronary disease undergoing coronary artery bypass grafting.
Timeline
- Start
- 2025-11-25
- Primary completion
- 2030-04-30
- Completion
- 2030-11-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Aspirin | Small molecule | 75 mg | Oral |
| Comparator | Aspirin | Small molecule | 300 mg | Oral |
| Subject | Prasugrel | Small molecule | 10 mg | Oral |