drugset / Trial / NCT07197684

Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surgery

NCT07197684

Not yet recruiting 120 enrolled Aga Khan University
RandomizedParallel-groupSingle-blindTreatment

Summary

The goal of this clinical trial is to is to compare the effectiveness of ultrasound-guided Pecs block with intravenous ketamine versus intravenous ketamine infusion alone in preventing Chronic Post-Surgical Pain (CPSP) in patients undergoing breast cancer surgery. The main question it aims to answer is, How effective is the ketamine and ketamine with pecs block in reducing the frequency of Chronic Post-Surgical Pain after breast cancer surgery

Timeline

Start
2026-03-16
Primary completion
2026-12-01
Completion
2027-05-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketamine Small molecule 0.25 mg/kg Intravenous
Background Acetaminophen Small molecule 15 mg/kg Intravenous
Background Acetaminophen Small molecule 1 g Intravenous
Background Nalbuphine Small molecule 0.1 mg/kg Intravenous