Chewing Gum vs. Ondansetron as Rescue Treatment for PONV in Female Patients

NCT07201883 ↗

Phase 1 Active not recruiting 90 enrolled Makassed General Hospital

RandomizedParallel-groupOpen-labelTreatment

Summary

The proposed randomized clinical trial aims to test and compare the efficacy of chewing gum vs. Intravenous antiemetic ondansetron as rescue treatment for post-operative nausea and vomiting (PONV) among Lebanese female patients undergoing laparoscopic surgery in the post-operative anesthesia care unit (PACU).

Timeline

Start: 2025-08-22
Primary completion: 2026-02-28
Completion: 2026-02-28

Publications

Results Chernik DA, Gillings D, Laine H, Hendler J, Silver JM, Davidson AB, Schwam EM, Siegel JL. Validity and reliability of the Observer's Assessment of Alertness/Sedation Scale: study with intravenous midazolam. J Clin Psychopharmacol. 1990 Aug;10(4):244-51.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Ondansetron	Other / unclassified	4 mg	Intravenous

Indications

No indication recorded.