drugset / Trial / NCT07213544
Remimazolam vs Propofol in Laser Burn Cases
RandomizedCrossoverSingle-blindTreatment
Summary
This randomized, single-blind, crossover study compares remimazolam and propofol for monitored anesthetic care during fractional ablative CO₂ laser therapy for burn scars. The primary aim is to assess incidence of respiratory depression, defined as a need for advanced airway maneuvers (jaw thrust/chin lift, insertion of oral or nasal airway, or bag mask ventilation), and hypopnea (respiratory rate \< 8).
Timeline
- Start
- 2025-11-12
- Primary completion
- 2027-01-01
- Completion
- 2027-01-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Propofol | Small molecule | 0.8 mg/kg | Intravenous |
| Comparator | Remimazolam | Small molecule | 0.075 mg/kg | — |
Indications
No indication recorded.