drugset / Trial / NCT07216482

A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)

NCT07216482

Phase 3 Active not recruiting 975 enrolled Merck Sharp & Dohme LLC
RandomizedFactorialTriple-blindTreatment

Summary

Researchers designed a study medicine called enlicitide to lower low-density lipoprotein cholesterol (LDL-C). In this study, researchers want to learn about giving enlicitide with another medicine called rosuvastatin. Rosuvastatin is a standard (usual) treatment to lower LDL-C. The goal of this study is to learn if enlicitide given with rosuvastatin works better than placebo on lowering LDL-C in a person's blood. A placebo looks like the study medicine but has no study medicine in it. Using a placebo helps researchers better understand the effects of a study medicine.

Timeline

Start
2025-11-11
Primary completion
2026-12-02
Completion
2027-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Enlicitide Unknown Oral
Subject Rosuvastatin Small molecule Oral

Indications