drugset / Trial / NCT07221019

Single Shot Exparel vs Catheters in Lower Extremity Trauma

NCT07221019 ↗

Phase 4 Recruiting 90 enrolled George Washington University
RandomizedParallel-groupOpen-labelSupportive care

Summary

This study will compare the use of single-shot Exparel, a long-acting local anesthestic, with the use of catheters that deliver a continuous flow of the short-acting local anesthetic ropivacaine. The comparison will be done in patients who receive preoperative adductor and sciatic nerve blocks prior to orthopedic surgery for traumatic lower extremity injury. The patients' pain will then be monitored for up to 72 hours after injection, measuring every 12 hours after injection until the 72-hour mark. Opioid consumption (measured in morphine milligram equivalents) will also be tracked over this time period.

Timeline

Start
2025-09-12
Primary completion
2028-08-11
Completion
2029-08-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Bupivacaine Other / unclassified 20 ml Other
Subject Bupivacaine Other / unclassified 50 ml Other

Indications

No indication recorded.