drugset / Trial / NCT07221149

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

NCT07221149

Phase 2/3 Recruiting 690 enrolled Bristol-Myers Squibb BioNTech SE · collab
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to evaluate the safety and efficacy of Pumitamig in combination with chemotherapy versus Nivolumab in combination with chemotherapy in participants with previously untreated advanced or metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma

Timeline

Start
2026-03-13
Primary completion
2030-11-08
Completion
2032-09-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Nivolumab Monoclonal antibody
Subject Pumitamig Protein / enzyme biologic