drugset / Trial / NCT07221617

Oral Methadone in Cardiac Surgery

NCT07221617

Phase 4 Recruiting 100 enrolled Mayo Clinic
RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to compare the effects of administration of oral methadone preoperatively and intravenous methadone upon induction of general anesthesia on postoperative pain for patients undergoing elective cardiac surgery.

Timeline

Start
2026-01-13
Primary completion
2026-06-30
Completion
2026-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Methadone Other / unclassified 0.3 mg/kg Oral
Comparator Methadone Other / unclassified 0.4 mg/kg Oral

Indications