drugset / Trial / NCT07221968

Melatonin for the Treatment of DEE-SWAS

NCT07221968

NaSingle-groupOpen-labelTreatment

Summary

The goal of this study is to learn if melatonin, a naturally produced substance, can help to treat some of the symptoms of DEE-SWAS, a type of epilepsy that causes children to lose skills and development. It will look at doses of melatonin that are higher than most people use. The study will look at the safety of melatonin in patients with DEE-SWAS The study will look at the ways melatonin affects abnormal brain activity on a study called an EEG. The study will look at the ways melatonin affects normal brain activity that occurs in sleep.

Timeline

Start
2026-07-01
Primary completion
2028-07-01
Completion
2028-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Melatonin Small molecule 0.3 mg/kg