drugset / Trial / NCT07223528

TEPH: Telaglenastat Efficacy in Pulmonary Hypertension

NCT07223528

Phase 1/2 Not yet recruiting 28 enrolled Chan, Stephen, MD, PhD Synhale Theraputics · collab
NaSingle-groupOpen-labelTreatment

Summary

The research study is being conducted to evaluate the effectiveness of a drug called Telaglenastat in adults diagnosed with Pulmonary Hypertension (PH). PH is a progressive condition that affects the arteries in the lungs, specifically the pulmonary arteries, which carry blood from the right side of the heart to the lungs. Telaglenastat is not currently approved by the Food and Drug Administration for the treatment of PH. However, the study investigators believe that Telaglenastat may help lower blood pressure in the lungs and improve both heart and lung function. It is important to note that the drug will not be available to participants once the study concludes.

Timeline

Start
2026-08
Primary completion
2028-09
Completion
2028-09

Drugs

EvaluationDrugModalityDoseRoute
Subject CB-839 Unknown 800 mg Oral