drugset / Trial / NCT07223671
Study to Evaluate the Effect of Repotrectinib on the Drug Levels of Transporter and CYP P450 Probe Substrates in Healthy Adult Participants
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The purpose of the study if to evaluate the effect of Repotrectinib on the drug levels of transporter and CYP P450 probe substrates in healthy adult participants.
Timeline
- Start
- 2025-12-31
- Primary completion
- 2026-02-19
- Completion
- 2026-03-19
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bupropion | Small molecule | — | — |
| Subject | Digoxin | Other / unclassified | — | — |
| Subject | Flurbiprofen | Small molecule | — | — |
| Subject | Metformin | Small molecule | — | — |
| Subject | Omeprazole | Other / unclassified | — | — |
| Subject | Repotrectinib | Small molecule | — | — |
| Subject | Rosuvastatin | Small molecule | — | — |
Indications
No indication recorded.