drugset / Trial / NCT07225946

A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

NCT07225946

Phase 3 Recruiting 800 enrolled Janssen Research & Development, LLC
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to find out whether treatment with pasritamig and docetaxel prolongs radiographic progression free survival (rPFS) (the length of time from start of treatment until disease worsens as determined by scans) when compared to treatment with docetaxel in participants with metastatic castrate-resistant prostate cancer (mCRPC; a cancer of prostate, a male reproductive gland found below the bladder, that grows despite low levels of male hormones).

Timeline

Start
2025-12-19
Primary completion
2027-11-19
Completion
2029-07-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Pasritamig Other / unclassified
Background Docetaxel Small molecule
Comparator Prednisone Other / unclassified