drugset / Trial / NCT07239011

Dapagliflozin in Depression

NCT07239011

Phase 1/2 Recruiting 60 enrolled Tanta University
RandomizedParallel-groupDouble-blindTreatment

Summary

Major depressive disorder (MDD) is currently one of the leading causes of disability and suicidal death worldwide, and despite extensive research and massive improvements in mental health, the nature of MDD remains ambiguous. Moreover, about two-thirds of MDD patients fail to optimally respond to currently available standard therapies, and many of them suffer from treatment-resistant depression

Timeline

Start
2025-11-01
Primary completion
2026-11-20
Completion
2026-12-20

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dapagliflozin Small molecule 10 mg
Comparator Fluoxetine Small molecule 20 mg

Indications