drugset / Trial / NCT07239011
Dapagliflozin in Depression
RandomizedParallel-groupDouble-blindTreatment
Summary
Major depressive disorder (MDD) is currently one of the leading causes of disability and suicidal death worldwide, and despite extensive research and massive improvements in mental health, the nature of MDD remains ambiguous. Moreover, about two-thirds of MDD patients fail to optimally respond to currently available standard therapies, and many of them suffer from treatment-resistant depression
Timeline
- Start
- 2025-11-01
- Primary completion
- 2026-11-20
- Completion
- 2026-12-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dapagliflozin | Small molecule | 10 mg | — |
| Comparator | Fluoxetine | Small molecule | 20 mg | — |