drugset / Trial / NCT07240649
Emerging Indications for Hyperbaric Oxygen Treatment
NaSingle-groupOpen-labelTreatment
Summary
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric Oxygen Treatment. The study team aims to collect ongoing data on how well HBOT treats these emerging indications, and to add these data to the growing HBO Registry. The research team hypothesizes that HBOT will result in improvements of the condition of the various emerging indications.
Timeline
- Start
- 2026-08
- Primary completion
- 2035-12
- Completion
- 2035-12
Publications
- Background Tanaka HL, Rees JR, Zhang Z, Ptak JA, Hannigan PM, Silverman EM, Peacock JL, Buckey JC; Multicenter Registry for Hyperbaric Oxygen Treatment Consortium. Emerging Indications for Hyperbaric Oxygen Treatment: Registry Cohort Study. Interact J Med Res. 2024 Aug 20;13:e53821. doi: 10.2196/53821.
- Background Harlan NP, Ptak JA, Rees JR, Cowan DR, Fellows AM, Moses RA, Kertis JA, Hannigan PM, Juggan SA, Peacock J, Bennett M, Buckey JC. International Multicenter Registry for Hyperbaric Oxygen Therapy: Results through June 2021. Undersea Hyperb Med. 2022 Third Quarter;49(3):275-287.
- Background Harlan NP, Ptak JA, Rees JR, Cowan DR, Fellows AM, Kertis JA, Hannigan PM, Peacock JL, Buckey JC. Development of an International, Multicenter, Hyperbaric Oxygen Treatment Registry and Research Consortium: Protocol for Outcome Data Collection and Analysis. JMIR Res Protoc. 2020 Aug 17;9(8):e18857. doi: 10.2196/18857.
- Background 1. Huang ET. Hyperbaric Medicine Indications Manual. 15th ed. North Palm Beach, FL: Best Publishing Company; 2023 2023. 445 p.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Oxygen | Other / unclassified | 100 % | Other |
Indications
COVID-19
Crohn disease
Raynaud disease
articular cartilage disorder
avascular necrosis
branch retinal artery occlusion
calciphylaxis
central retinal vein occlusion
chronic cystitis
decubitus ulcer
enterocolitis
epidermolysis bullosa
fungal infectious disease
graft versus host disease
hypospadias
inclusion body myositis
intestinal fistula
ischemic bowel disorder
ligament disorder
malignant otitis externa
multiple sclerosis
non-arteritic anterior ischemic optic neuropathy
peripheral nerve lesion
pneumatosis cystoides intestinalis
post-COVID-19 disorder
pouchitis
prosthesis-related infectious disease
pterygium
pyoderma gangrenosum
tinnitus
traumatic brain injury
ulcer of anus and rectum
ulcerative colitis
vasculitis