drugset / Trial / NCT07247097

ELDORADO: Elranatamab Versus Daratumumab in Combination With RVd Lite for Newly Diagnosed Transplant Ineligible/Deferred Multiple Myeloma

NCT07247097

Phase 2 Not yet recruiting 160 enrolled Massachusetts General Hospital Pfizer · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

This research study is being done to compare the efficacy and safety of the combination of elranatamab, lenalidomide, bortezomib, dexamethasone versus the combination of daratumumab, lenalidomide, bortezomib, dexamethasone for patients with newly diagnosed, transplant ineligible/deferred multiple myeloma.

Timeline

Start
2026-08-01
Primary completion
2030-12-01
Completion
2035-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Daratumumab Monoclonal antibody Subcutaneous
Subject Elranatamab Monoclonal antibody Subcutaneous
Background Bortezomib Small molecule Subcutaneous
Background Dexamethasone Small molecule Oral
Background Lenalidomide Other / unclassified Oral

Indications