drugset / Trial / NCT07257198

Aspirin-free Strategy With Ticagrelor in Patients With a Myocardial Infarction Treated Medically Alone

NCT07257198

Phase 3 Recruiting 2570 enrolled Montreal Heart Institute
RandomizedParallel-groupQuadruple-blindTreatment

Summary

In patients with a myocardial infarction (MI) treated medically alone, the objective of the PANTHEON trial is to evaluate if ticagrelor monotherapy reduces bleeding events, without an increase in patient-oriented ischemic events, compared with standard dual antiplatelet therapy (DAPT) with aspirin and ticagrelor for 12 months.

Timeline

Start
2026-03-03
Primary completion
2030-01-01
Completion
2031-01-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Aspirin Small molecule 80 mg Oral
Comparator Ticagrelor Small molecule 90 mg Oral