Erector Spinae Plane Block and Postoperative Recovery After Open-Heart Surgery

Summary

This prospective randomized controlled clinical trial evaluated the effects of bilateral erector spinae plane block (ESPB) on postoperative systemic functions in adult patients undergoing elective open-heart surgery via median sternotomy. Sixty-six participants were randomized to receive either bilateral ultrasound-guided ESPB before anesthesia induction or standard intravenous opioid analgesia. Postoperative outcomes-including pain scores, rescue analgesic requirements, hemodynamic parameters, respiratory variables, and laboratory values-were monitored for forty-eight hours. The study was conducted to determine whether ESPB provides improved postoperative pain control and supports systemic recovery compared with intravenous opioid-based analgesia.

Timeline

Start

2023-01-30

Primary completion

2024-06-30

Completion

2024-08-20

Publications

• Results Sarica F, Erturk E, Kutanis D, Akdogan A, Senel AC. Comparison of Thoracic Epidural Analgesia and Traditional Intravenous Analgesia With Respect to Postoperative Respiratory Effects in Cardiac Surgery. J Cardiothorac Vasc Anesth. 2021 Jun;35(6):1800-1805. doi: 10.1053/j.jvca.2020.09.110. Epub 2020 Sep 20.
• Results Oostvogels L, Weibel S, Meissner M, Kranke P, Meyer-Friessem CH, Pogatzki-Zahn E, Schnabel A. Erector spinae plane block for postoperative pain. Cochrane Database Syst Rev. 2024 Feb 12;2(2):CD013763. doi: 10.1002/14651858.CD013763.pub3.
• Results Shan XS, Liao DW, Guo J, Xia ZY, Lv X, Shen J, Tong JH, Wei FJ, Li XS, Qu XF, Wang XB, Wang YB, Ou SS, Yang YF, Meng L, Liu H, Peng K, Ji FH. Effect of liposomal bupivacaine for preoperative erector spinae plane block on postoperative pain following video-assisted thoracoscopic lung resection: a multicenter, randomized, double-blind, clinical trial. Int J Surg. 2026 Feb 1;112(2):3690-3700. doi: 10.1097/JS9.0000000000003956. Epub 2025 Nov 11.

Drugs

Indications

No indication recorded.