drugset / Trial / NCT07265297

Using Hydroxychloroquine (HCQ) to Treat Steatohepatitis

NCT07265297

Phase 3 Recruiting 210 enrolled National Taiwan University Hospital
RandomizedParallel-groupTriple-blindTreatment

Summary

The goal of this clinical trial is to learn if drug hydroxychloroquine works to treat steatohepatitis in adults. It will also learn about the safety of drug hydroxychloroquine. The main questions it aims to answer are: Does drug hydroxychloroquine improve steatohepatitis? What medical problems do participants have when taking drug hydroxychloroquine? Researchers will compare drug hydroxychloroquine to a placebo (a look-alike substance that contains no drug) to see if drug hydroxychloroquine works to treat steatohepatitis. Participants will: Take drug hydroxychloroquine 400mg or hydroxychloroquine 200mg or placebo every day for 12 months Visit the clinic once every 3 months for checkups and tests

Timeline

Start
2025-08-12
Primary completion
2030-12-31
Completion
2030-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Hydroxychloroquine Small molecule 200 mg
Subject Hydroxychloroquine Small molecule 400 mg

Indications