drugset / Trial / NCT07268170

Heart Rate Control Before Cardiac Computed Tomography in Adults for the Evaluation of Coronary Artery Disease

NCT07268170

Phase 2/3 Enrolling by invitation 350 enrolled Gødstrup Hospital
RandomizedParallel-groupTriple-blindTreatment

Summary

The goal of this clinical trial is to describe which type and dose of commonly used heart rate reducing drugs (metoprolol, atenolol, or ivabradine) has the swiftest heart rate reduction from baseline in patients aged 30 to 80 years with a heart rate \> 65 beats per minute undergoing cardiac computed tomography for the evaluation of coronary artery disease. The main question it aims to answer is • Which type of heart reducing drug and dose has the swiftest heart rate reduction before cardiac computed tomography?

Timeline

Start
2025-12-15
Primary completion
2028-09-01
Completion
2028-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Atenolol Other / unclassified 50 mg
Subject Atenolol Other / unclassified 100 mg
Subject Ivabradine Small molecule 7.5 mg
Subject Ivabradine Small molecule 15 mg
Subject Metoprolol Other / unclassified 50 mg
Subject Metoprolol Other / unclassified 100 mg