drugset / Trial / NCT07269782

A Phase II Study to Evaluate the Efficacy and Safety of HLX43 + Serplulimab as Neoadjuvant Therapy in Subjects With NSCLC

NCT07269782

Phase 2 Recruiting 60 enrolled Shanghai Henlius Biotech
RandomizedParallel-groupOpen-labelTreatment

Summary

The study is being conducted to to explore the reasonable dosage and evaluate the efficacy and safety of HLX43 (Anti-PD-L1 ADC) in Combination with Serplulimab (Anti-PD-1 Recombinant Humanized Monoclonal Antibody) as Neoadjuvant Therapy in Subjects with Non-Small Cell Lung Cancer (NSCLC)

Timeline

Start
2026-01-20
Primary completion
2026-07-10
Completion
2026-11-30

Drugs

EvaluationDrugModalityDoseRoute
Subject HLX43 Other / unclassified Intravenous
Subject Serplulimab Monoclonal antibody Intravenous