drugset / Trial / NCT07283692

Neoadjuvant Serplulimab Plus Weekly Paclitaxel and Carboplatin in TNBC (Neo-SERPENT)

NCT07283692

Phase 2 Recruiting 46 enrolled RenJi Hospital
NaSingle-groupOpen-labelTreatment

Summary

This is an prospective, open label, multicenter study to evaluate the efficacy and safety of neoadjuvant serplulimab plus weekly paclitaxel and carboplatin in patients with triple-negative breast cancer.

Timeline

Start
2026-03-01
Primary completion
2026-12
Completion
2031-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule
Subject Paclitaxel Small molecule 80 mg/m2
Subject Serplulimab Monoclonal antibody 1.5 mg/kg